If possible, wet-age the meat in the fridge for 2-3 weeks in the Crayovac bag it came in.
Place the rub ingredients in a medium bowl and mix well. Apply the rub to the chuck roast in an even layer. Refrigerate for at least a few hours and up 48 hours for best results. Keep the meat in a Ziploc bag if refrigerating for longer than a few hours, flipping once halfway though. Otherwise, keep the meat uncovered.
Preheat the smoker to 275F. Smoke with oak or hickory for about 4 hours or until the internal temperature reaches about 165F and the meat develops a dark color.
Take the roast out of the smoker, wrap it tightly in unglazed butcher paper, and return to the smoker.
Continue cooking the meat in the smoker without the smoke at 325F for another 3-4 hours or until the internal temperature of the roast reaches 203F - 210F.
After the meat is done cooking, remove it from the smoker and let it rest, wrapped, for about 1 hour or until the internal temperature comes down to about 145F. Then unwrap, slice/pull, and serve.
If you are impatient like me, unwrap right away, but be careful as it will be steaming hot. Then, slice the meat and make the most amazing smoked chuck sandwiches you will ever taste.